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Ketoconazole is in a class of antifungal medications called imidazoles. It works by inhibiting the growth of fungi that cause the infection. Topical ketoconazole is indicated for the treatment of cutaneous candidosis (including vulvitis), tinea (pityriasis) versicolor and seborrhoeic dermatitis caused by Malassezia (previously called Pi...
International Journal of Research in Dermatology: March, 2022Tinea caused by trichophyton,    microsporum,    and epidermophyton is the most common fungal infection affecting   20–25%   population globally,   with varying geographic distribution.Due to  Bangladesh’s hot and humid cli...
The prevalence of superficial fungal infections across the globe is increasing from 20-25%. Superficial infections are mostly caused by dermatophytes. Depending on the site affected, the dermatophytes are clinically classified as Tinea capitis (head), Tinea faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body), Tinea c...
There has been a significant increase in the incidence of chronic, relapsing, recurrent cases of superficial dermatophytosis in India that are also often unresponsive to conventional drugs and doses of recommended antifungal treatment. Almost 15– 20% of the outpatient department cases are those of chronic dermatophytosis. Recurrences and relaps...
Mycoses Journal: Published on April 2021Dermatomycoses of zoophilic origin, especially those caused by Trichophyton mentagrophytes, often pose considerable therapeutic problems. This is reflected in the growing number of strains of this species with resistance to terbinafine caused by a mutation in the squalene epoxidase (SQLE) gene. TAKE HOME...
PubMed Central: November, 2022Tinea versicolor is a common superficial fungal infection of the skin with various clinical manifestations. This review aims to familiarize physicians with the clinical features, diagnosis and management of tinea versicolor.Tinea versicolor is caused by Malassezia species, notably M. globosa, M....
Infection and Drug Resistance Journal:Tinea is superficial fungal infections typically caused by dermatophytes.Superficial fungal infections are widespread, with an estimated worldwide prevalence of 20%–25%, and include tinea pedis (athlete’s foot), tinea cruris (jock itch), and tinea corporis (ringworm), among othersTopical allylamine (terbinaf...
Indian Journal of Pharmacology: Published: May, 2019Dermatophytic infections are the common fungal infections aggravated by hot and humid climate. Terbinafine and Itraconazole are commonly used oral antifungal agents for the same. However, resistance to these drugs is being seen increasingly when used in the conventional doses and duration. In...
Principles of TherapyTopical AntifungalsTopical medications have better pharmacokinetics than their systemic counterparts. Hence, the combination is expected to have better mycological clearance than systemic and topical alone. The combination should be from different groups for wide coverage and also to prevent the emergence of resistance. Dru...
Superficial fungal infections are primarily caused by dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the world’s population.The lesion of dermatophytosis is present with an annular or ring-shaped red scaly plaque with central clearing, often associated with severe pruritus.Systemic or topical antifungal drugs are used as...
International Journal of Research in Dermatology: Published on February, 2021Dermatophytic infections are the most prevalent fungal infections, which affect majority of the global population. Indian climate, especially the hot and humid conditions contribute majorly to dermatophytosis. Azoles are the most commonly used antifungal agents due  t...
European Journal of Molecular & Clinical Medicine: Published on 2020Superficial infection caused by a dermatophyte is termed dermatophytosis or ringworm. They are all moulds belonging to three asexual genera: microsporum, trichophyton and epidermophyton.Depending upon the site of infection, dermatophyte infection can be classified as...