The prevalence of superficial
fungal infections across the globe is increasing from 20-25%. Superficial
infections are mostly caused by dermatophytes. Depending on the site affected,
the dermatophytes are clinically classified as Tinea capitis (head), Tinea
faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body),
Tinea cruris (groin), Tinea pedis (foot), and Tinea unguium (nail).
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This current study aims to evaluate
the effectiveness of luliconazole in real-world settings. In the
present study, 1% luliconazole was prescribed for four weeks maybe due to the
prolonged duration of the infections as most of the patients had complaints of
infections for 4-5 weeks or more.
Topical therapy is an accepted
method of treatment for superficial infections caused by dermatophytes. Oral
agents are reserved for severe or recalcitrant cases.
The topical application of azole
antifungal agents has been proved as an effective treatment.
Newer therapy aimed at antifungals
with a longer duration of action and once daily dosing is recommended.
Longer duration of treatment with
old generation topical antifungal agents usually triggers the patient
non-adherence which in turn raises the chances of disease relapse.
Luliconazole, an antifungal agent,
has shown promising results in clinical trials within short duration of
treatment has greater patient compliance and is effective for treatment of
Tinea pedis, Tinea cruris, and Tinea corporis caused by T. rubrum and E.
floccosum
In the current study, the
infections were mainly Tinea cruris and Tinea corporis. A complete clearance
(mycological cure and clinical cure) in 95% patients marked the recovery.
Luliconazole demonstrated effectiveness in the treatment of Tinea corporis, Tinea cruris and Tinea pedis.
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