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During the holy month of Ramadan, Muslims practice daily fasting from dawn to sunset. This commitment changes their daily food routine in terms of number of meals, quantity of caloric intake, and types of food consumed. This change in consumption patterns during Ramadan has an effect on metabolism and weight, sleeping patterns, and possibly ga...
Gastro-esophageal reflux disease (GERD) is a disorder involving troublesome symptoms associated with persistent reflux of gastric contents into the esophagus. Symptoms include heartburn, cough, epigastric pain, vomiting, and regurgitation.GERD is proposed to have 5 distinct presentations—nonerosive GERD (NERD), erosive esophagitis (EE), functio...
TAKE-HOME MESSAGEAbout 80% of pregnant women suffer from gestational reflux disease. Most interventions are based on a “step-up” approach that begins with lifestyle modifications. If the symptoms persist despite lifestyle modification, a medical intervention can be considered. Antacids, alginates and sucralfate are the first-line t...
BioMed Central (BMC) Gastroenterology Journal: Gastroesophageal reflux disease (GERD) is one the most common medical complaints in pregnant women. Its prevalence has been reported to reach as high as 80% in certain populations. The prevalence of GERD is also increased as pregnancy progresses from the first to third trimester. Some women...
TAKE-HOME MESSAGE The authors of this meta-analysis evaluated the efficacy of alginate-containing compounds for the treatment of gastroesophageal reflux disease (GERD) symptoms. The odds of resolution of GERD symptoms was significantly greater with alginate-based therapies than with placebo or antacids. Alginate therap...
Antacids neutralize gastric acid and are, broadly used in the treatment of gastroesophageal reflux disease (GERD) in adults. They are utilized for more than 2,000 years, though evidence of the effectiveness and safety is limited in infants [1]. Antacids have an effect on the short-term relief of heartburn and the healing of esophagitis. Charac...
Many women experience heartburn during pregnancy. It can be extremely uncomfortable and can negatively affect women’s experience of pregnancy and their quality of life.Dietary changes may help to reduce or stop heartburn. The NICE guideline on gastrooesophageal reflux disease and dyspepsia in adults includes recommendations about dietary and l...
Medical management of GERD mainly uses proton pump inhibitors. Alginates plus Antacids also have proven efficacy. Tolerance and safety were good and comparable in both groups.Alginates plus Antacids was non-inferior to omeprazole in achieving a 24-h heartburn-free period in moderate episodic heartburn, and is a relevant effective alternative tr...
A Double Action Antacid & Alginate Liquid was more effective than an antacid in controlling postprandial esophageal acid exposure in GERD patients. This suggests that this main effectiveness related to its co-localization with and displacement/neutralization of the post-prandial acid pocket, rather than preventing reflux.Heartburn is...
Many reflux patients remain symptomatic on a standard dose of proton pump inhibitor (PPI). In some patients, especially those with nonerosive reflux disease or atypical GERD symptoms, acid-suppressive therapy with PPIs is not as successful. In patients with residual reflux symptoms despite PPI treatment, adding an alginate plus antacid offe...