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Due to the changing face of dermatophytosis in India, many dermatologists practice different dosing patterns of itraconazole (ITZ). Recently, a new form of ITZ, super-bioavailable ITZ (SBITZ), has been commercialized to overcome the pharmacokinetic challenges of conventional ITZ (CITZ). ITZ is a weak base lipophilic molecule with a limite...
The prevalence of superficial fungal infections across the globe is increasing from 20-25%. Superficial infections are mostly caused by dermatophytes. Depending on the site affected, the dermatophytes are clinically classified as Tinea capitis (head), Tinea faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body), Tinea c...
There has been a significant increase in the incidence of chronic, relapsing, recurrent cases of superficial dermatophytosis in India that are also often unresponsive to conventional drugs and doses of recommended antifungal treatment. Almost 15– 20% of the outpatient department cases are those of chronic dermatophytosis. Recurrences and relaps...
Infection and Drug Resistance Journal:Tinea is superficial fungal infections typically caused by dermatophytes.Superficial fungal infections are widespread, with an estimated worldwide prevalence of 20%–25%, and include tinea pedis (athlete’s foot), tinea cruris (jock itch), and tinea corporis (ringworm), among othersTopical allylamine (terbinaf...
International Journal of Scientific Study (IJSS): May, 2020Superficial fungal infections are caused by dermatophytes, non-dermatophytic molds, and commensal yeasts. According to published literature, the global prevalence rate of superficial mycotic infection has been found to be 20–25%. The recent prevalence of dermatophytosis in India ranges f...
The British Journal of DermatologyDermatophytic infections have undergone unprecedented changes in India in the recent past. Oral antifungal drugs are considered to have a high cure rate in tinea corporis, tinea cruris and tinea faciei.Clinical trials to find out the effectiveness of the four main oral antifungal drugs are lacking.Authors teste...
Superficial fungal infections are primarily caused by dermatophytes, Candida spp, and Malassezia species affects 20%–25% of the world’s population.The lesion of dermatophytosis is present with an annular or ring-shaped red scaly plaque with central clearing, often associated with severe pruritus.Systemic or topical antifungal drugs are used as...
Clinicians should be more judicious in prescribing or recommending oral or topical antifungal therapy.Given the limited selection of antifungals, it is paramount to mitigate resistant cases. Mitigation proposals include:·              good skin hygiene,·    &nb...
International Journal of Research in Dermatology: Published on February, 2021Dermatophytic infections are the most prevalent fungal infections, which affect majority of the global population. Indian climate, especially the hot and humid conditions contribute majorly to dermatophytosis. Azoles are the most commonly used antifungal agents due  t...
The Journal of Dermatology:Luliconazole Cream, 1% is an azole antifungal indicated for the topical treatment of interdigital tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum and Epidermophyton floccosum.TAKE HOME MESSAGES: Authors evaluated the efficacy and safety of luliconazole cream 1% in the treatmen...
Published on Infection and Drug Resistance Journal:Tinea is superficial fungal infections typically caused by dermatophytes. Common pathogens include Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. Superficial fungal infections are widespread, with an estimated worldwide prevalence of 20%–25%, and include tinea p...