Drug-highlights
AGA Gastroenterology Journal: Published on November, 2022In adults, obesity-related
complications, such as cardiovascular disease, stroke, type 2 diabetes mellitus
(T2DM), nonalcoholic steatohepatitis, obstructive sleep apnea, osteoarthritis,
and certain types of cancer (eg, colorectal cancer), have also increased,
contributing to high morbidit...
Gastro-esophageal reflux disease
(GERD) is a disorder involving troublesome symptoms associated with persistent reflux
of gastric contents into the esophagus. Symptoms include heartburn, cough,
epigastric pain, vomiting, and regurgitation.GERD is proposed to have 5 distinct
presentations—nonerosive GERD (NERD), erosive esophagitis (EE), functio...
Mycoses Journal: Published on April 2021Dermatomycoses of zoophilic origin,
especially those caused by Trichophyton mentagrophytes, often pose considerable
therapeutic problems. This is reflected in the growing number of strains of
this species with resistance to terbinafine caused by a mutation in the
squalene epoxidase (SQLE) gene. TAKE HOME...
Neurology: August, 2023Cumulative use of proton pump
inhibitors (PPIs) for more than 4.4 years is associated with an increased risk
for dementia, according to a study published in Neurology.TAKE-HOME MESSAGEThis study
evaluated whether the current and cumulative use of proton pump inhibitors
(PPIs) are associated with a higher risk of incident...
Clinical Gastroenterology and Hepatology: February,
2022The incidence rate of
hepatocellular carcinoma (HCC) has been increasing for the last 3 decades. Fatty liver
progresses from fat accumulation to inflammation to fibrosis to cirrhosis to
cancer. Recent evidence suggests potential clinical
benefits of statin in cancer chemoprevention a...
AGA Journals (Gastroenterology): June, 2023Chronic idiopathic constipation
(CIC) is a common disorder associated with significant impairment in quality of
life. This clinical practice guideline,
jointly developed by the American Gastroenterological Association and the
American College of Gastroenterology, aims to inform clinicians and patients...
Reviews in Endocrine and Metabolic Disorders: Published:
August 2021Endometriosis is a chronic disease
characterized by the presence of endometrium-like tissue outside the uterine
cavity, affecting women of reproductive age with pelvic pain and infertility deeply
affecting women’s health. The most common symptoms of
endometriosis are menstruat...
American Journal of Ophthalmology: Published May, 2023Glaucoma is a disease characterized
by progressive deterioration of the optic nerve and retinal nerve fiber
layer (RNFL) defect with corresponding visual field changes.Globally, both the prevalence of
chronic kidney disease (CKD) and glaucoma are rising rapidly. These 2 diseases
share a comm...
JAMA Network: November, 2019Proton pump inhibitors (PPIs) are
drugs widely prescribed to reduce gastric acidity. Although they are considered
globally safe, observational studies have reported significant
adverse effects associated with their long-term use, such as
osteoporotic-related fractures, vitamin B12 deficiency, kidney
disease, or...
Tinea (pityriasis) versicolor is a
superficial fungal infection and one of the most commonly found pigmentary
disorders of skin caused by the yeast Malassezia. Multiple topical as well as
systemic therapies are available for treatment. Systemic therapies are used for
extensive disease, frequent relapse or where topical agents have failed. TAKE...
Human Reproduction Update Journal: Published on February, 2019Subclinical hypothyroidism (SCH) is
defined as an elevated serum thyrotropin (TSH) level with normal serum
thyroxine (T4) level and affects 3–8% of women of childbearing age. International guidelines advocate
the use of population-based reference ranges of TSH during pregnancy; h...
CHRISMED Journal of Health and Research: Published
on 2019Dysfunctional uterine bleeding
(DUB) is excessive uterine bleeding which is not attributed to pregnancy or any
detectable uterine or systemic pathology. Patients suffering from DUB
commonly complain about heavy menstrual bleeding (HMB), irregular bleeding,
spotting between periods, or s...
