Infectious-diseases

Probiotics are live microorganisms that confer health benefits when consumed in adequate amounts, including enhanced immune activity and the clearance of respiratory tract infections. (FAO and WHO, UN).  Probiotics could be used as an adjunctive treatment against COVID-19.Role of probiotics to combat COVID-19It is evident that probiotics ca...
Coronaviruses—by the very nature of their RNA-based genome—have an intrinsically higher rate of mutation than DNA-based viruses. That said, they manifest a lower rate of mutation than influenza viruses due to the presence of genetic code for an enzyme that corrects some transcription errors. Mutations naturally arise during viral replicati...
The COVID-19 Treatment Guidelines have been developed to inform clinicians how to care for patients with COVID-19. Because clinical information about the optimal management of COVID-19 is evolving quickly. The recommendations in these Guidelines are based on scientific evidence and expert opinion. Each recommendation includes two...
This guidance document is intended for clinicians caring for COVID-19 patients during all phases of their disease (i.e., screening to discharge).  This update has been expanded to meet the needs of front-line clinicians and promotes a multi-disciplinary approach to care for patients with COVID-19, including those with mild, moderate, severe, a...
What do we know about this new SARS-CoV-2 variant? It’s been snappily named VUI-202012/01 (the first “Variant Under Investigation” in December 2020) and is defined by a set of 17 changes or mutations. One of the most significant is an N501Y mutation in the spike protein that the virus uses to bind to the human ACE2 receptor. Changes in this...
In a clinical trial of patients with COVID-19, monoclonal antibody were shown to reduce COVID-19-related hospitalization or emergency room visits in patients at high risk for disease progression within 28 days after treatment when compared to placebo. The safety and effectiveness of this investigational therapy for use in the treatment of C...
FDA Authorizes Monoclonal Antibody for Treatment of COVID-19. The U.S. FDA issued an emergency use authorization (EUA) for the investigational monoclonal antibody therapy for the treatment of mild-to-moderate COVID-19 in adult and pediatric patients.
Dexamethasone : the first life-saving drug for COVID-19 patients Clinical trials make it possible to evaluate whether a treatment improves outcomes. Developing a hypothesis, for example if treatment A is better than standard treatment B, clinical trials enable understanding of the role of an intervention in improving patient care. In the...
National guidelines version 8th on clinical management of Coronavirus disease by Disease Control Division, Directorate General of Health Services, Ministry of Health & Family Welfare & Government of the People's Republic of Bangladesh. The guideline includes clinical management of COVID-19 and is updated with the latest evide...
An Aid to the Management of COVID-19 in Bangladesh: “Lessons from the western experience” New 5th Edition This book is a small effort by some highly-motivated Bangladeshi doctors living in the UK and the USA to supplement local guidelines in Bangladesh. This will hopefully enable local experts in Bangladesh to be kept updated...
National guidelines on clinical management of Coronavirus disease by Disease Control Division, Directorate General of Health Services, Ministry of Health & Family Welfare & Government of the People's Republic of Bangladesh.The guideline includes clinical management of COVID-19 and is updated with the latest evidence and the WHO guidelines.