Gynecology-obstetrics-disorders

Key Information: Progesterone is essential for the maintenance of a healthy pregnancy. Progesterone is frequently prescribed to patients presenting with per vaginal (PV) bleeding in early pregnancy and a history of recurrent pregnancy loss. Any defect in the secretion of human chorionic gonadotropin or progesterone is associated with...
Take Home Message: Endometriosis is estimated to affect 10–15% of women of childbearing age and as much as 15–30% of those with primary or secondary infertility. Endometriosis associated pelvic pain (EAPP) is the most common complaint of patients with endometriosis. It occurs when endometrial cells proliferate outside the uterus, for...
Combined oral contraceptives (COC) and progestogens are widely used for the treatment of endometriosis. TAKE HOME MESSAGE This study was carried out to compare the effect of dienogest (2mg) vs a combined oral contraceptive (levonorgestrel 0.1mg/ethinyl estradiol 0.02mg) on ovarian endometriomas, deep infiltrating endometriosis (DIE),...
The Journal of Obstetric and Gynecological Research: Miscarriage is the most common cause of early pregnancy loss in the first 24 weeks and one of the most common complications in early pregnancy. An estimated 15% to 20% of pregnancies will end in a miscarriage, with 25% of women experiencing a miscarriage in their lifetime. Women can b...
Endometriosis is defined as the presence of endometrium-like tissue outside the uterus. It causes a chronic inflammatory reaction that may result in the formation of scar tissue (adhesions, fibrosis) within the pelvis and other parts of the body. It is a chronic disease associated with severe, life-impacting pain during periods, sexual...
The British Medical Journal (BMJ): Increasing evidence suggests that reproductive factors unique to women are associated with a greater risk of death from non-communicable diseases. Even if reproductive events do not increase the risk of death from non-communicable diseases, they could be useful as an early stress test of underlying risk...
Successful oocyte implantation and a favorable pregnancy outcome rely on optimal progesterone levels. Therefore, progesterone deficiencies associated with infertility and miscarriages have commonly been treated with progestogens that mimic the activity of progesterone. Among those is dydrogesterone, an oral retrosteroid with a structur...
The Journal of Obstetrics & Gynecology Research: An ovarian endometrioma is a cystic mass arising from ectopic endometrial tissue within the ovary. It contains thick, brown, tar-like fluid, which may be referred to as a "chocolate cyst." Endometriomas are often densely adherent to surrounding structures, such as the peritoneum, fallopian...
Global Journal of Reproductive Medicine: Endometriosis is a common disease in up to 10% of women of reproductive age. It often causes symptoms such as dysmenorrhea, chronic pelvic pain, dyspareunia and dyschezia. It is also associated with ovarian endometrioma which requires surgery for both diagnosis and treatment. However, recurrence r...
Threatened miscarriage is the most common complication in the first half of pregnancy affecting 20-25% of women. Diagnosis of threatened miscarriage is established when there is a viable pregnancy with vaginal bleeding and a closed cervix. Any woman who presents with threatened miscarriage; ultrasound imaging is performed to ascertain th...
Journal of the Women’s Health: Published on April 2021 Endometriosis is an estrogen-dependent, inflammatory condition marked anatomically by the presence of extrauterine lesions containing endometrial glands and stroma. Affecting an estimated 6%–10% of women, endometriosis is one of the most common gynecologic conditions among reproduct...
JAMA Network Anemia is the most widespread nutritional deficiency among pregnant females in the world. A total of 40.05% of pregnant females worldwide had anemia during pregnancy, with the highest prevalence (48.15%) in Southeast Asia. Because of the high prevalence of anemia, any adverse maternal and fetal outcomes associated with...