Gynecology-obstetrics-disorders

Treatment for Mild Chronic Hypertension during Pregnancy
The New England Journal of Medicine (NEJM): Published on April, 2022Antihypertensive treatment during pregnancy reduces the frequency of severe hypertension (blood pressure, ≥160/110 mm Hg) but has not been shown to improve maternal, fetal, or neonatal outcomes and has been associated with an increased risk of small-for-gestational-age birth w...
Efficacy of Dienogest for Prevention of Endometriosis Recurrence
MIDDLE EAST JOURNAL OF FAMILY MEDICINE: Published on November, 2022A Systematic Review and Meta-AnalysisEndometriosis is a chronic, estrogen-dependent disease that affects 10-15% of women in their reproductive age. It is characterized by the presence of endometriallike tissues outside the uterine cavity that induce chronic inflammation, ovarian...
How does subchorionic hematoma in the first trimester affect pregnancy outcomes?
PubMed Central: Published on January, 2021Subchorionic hematoma (SCH) refers to a collection of blood between the chorionic membrane and the uterine wall as caused by the separation of the chorion from the endometrium. It is the most common sonographic abnormality in pregnant women with symptoms of threatened miscarriage and the most common cau...
Safety of Booster Doses of COVID-19 Vaccine in Pregnancy
Obstetrics and Gynecology Journal: Published in September, 2022Vaccination against coronavirus disease 2019 is safe and effective at preventing illness, including hospitalization and death due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, and booster and additional primary dose COVID-19 vaccinations increase protec...
Gestational Glucose Intolerance and Risk of Future Diabetes
Diabetes Care Journal: Published on January 2023Gestational diabetes (GDM) is a complex disorder associated with adverse fetal and maternal outcomes. GDM is a global problem and has an estimated prevalence of 14%. The term gestational glucose intolerance (GGI) is applied to women who have an abnormal screening 50-g glucose challenge test (...
Long-Term Safety and Efficacy of Elagolix Treatment in Women with Endometriosis-Associated Pain
American College of Obstetricians and Gynecologists (ACOG): Endometriosis is a chronic, estrogen-dependent condition that causes dysmenorrhea and pelvic pain that affects 6–10% of women of reproductive age. Elagolix is an oral, nonpeptide Gonadotropin-releasing hormone (GnRH) antagonist suppressed estradiol production in a dose-depend...
Dysmenorrhea, Endometriosis and Chronic Pelvic Pain in Adolescents
The majority (70-93%) of adolescents have discomfort associated with menstruation. Dysmenorrhea is the most common reason for missed school and activities. Up to 20-40% report missed school due to dysmenorrhea, and 40% report a negative effect on school performance and concentration. Adolescents with severe dysmenorrhea have impaired qualit...
Use of Dienogest in endometriosis: Expert Commentary
Endometriosis affects up to 10% of women of reproductive age, and the main goal of treatment is to relieve symptoms. Progestins have been the mainstay of endometriosis suppression, of which dienogest has become an important option in many parts of the world.   A search of PubMed was conducted for papers published between 2007–2019 o...
Pretreatment with Dienogest in women with Endometriosis undergoing IVF after a previous failed cycle
Endometriosis is a benign chronic inflammatory estrogen-dependent disease and a well-known cause of infertility. Endometriosis may have a direct harmful effect on fertility not only due to the presence of adhesions and anatomic distortions, but also because of the intrinsic negative impact on oocyte development, embryogenesis, or implantat...
Diagnosing adenomyosis: An integrated clinical and imaging approach
Pathogenesis of adenomyosis involves sex steroid hormone abnormalities, inflammation, fibrosis and neuro angiogenesis, even though the proposed mechanisms are not fully understood. Nowadays, adenomyosis may also be diagnosed by non-invasive techniques, because of imaging advancements.     Adenomyosis often coexists with other gynecologic...
Subchorionic Hematoma accounts for 20% of all bleeding during the 1st trimester of pregnancy
Any type of bleeding during pregnancy can be alarming. About 25% of women experience some bleeding or spotting during their pregnancy. Subchorionic hematomas are the cause of about 20% of all bleeding during the first trimester. This is a type of bleeding that occurs between amniotic membranes. It occurs when the placenta partially detaches...
Effect of Dydrogesterone and Progesterone on threatened miscarriage due to corpus luteum insufficiency
PubMed Central: IntroductionThreatened miscarriage is a common disease during early pregnancy, with a morbidity of 30% to 40%, which could develop into a complete miscarriage or dystocia without timely treatment. Many pathogenic factors contribute to the threatened miscarriage, of which lacking progestogens due to the endocrine dysfunction of...