Dermatologic-disorders
The prevalence of superficial
fungal infections across the globe is increasing from 20-25%. Superficial
infections are mostly caused by dermatophytes. Depending on the site affected,
the dermatophytes are clinically classified as Tinea capitis (head), Tinea
faciei (face), Tinea barbae (beard), Tinea manus (hand), Tinea corporis (body),
Tinea c...
JAMA: The Journal of the American Medical AssociationThe authors investigated different
oral antifungal medications used to treat toenail fungal infections.TAKE-HOME MESSAGECompared
with placebo, high-quality evidence supports better clinical (ie, normal
appearance of the toenail) and mycological (negative culture, microscopy, or
both) results...
There has been a significant
increase in the incidence of chronic, relapsing, recurrent cases of superficial
dermatophytosis in India that are also often unresponsive to conventional drugs
and doses of recommended antifungal treatment. Almost 15– 20% of the outpatient
department cases are those of chronic dermatophytosis. Recurrences and relaps...
Mycoses Journal: Published on April 2021Dermatomycoses of zoophilic origin,
especially those caused by Trichophyton mentagrophytes, often pose considerable
therapeutic problems. This is reflected in the growing number of strains of
this species with resistance to terbinafine caused by a mutation in the
squalene epoxidase (SQLE) gene. TAKE HOME...
PubMed Central: November, 2022Tinea versicolor is a common superficial fungal infection of
the skin with various clinical manifestations. This review aims to familiarize
physicians with the clinical features, diagnosis and management of tinea
versicolor.Tinea versicolor is caused by Malassezia species,
notably M. globosa, M....
Infection and Drug Resistance Journal:Tinea is superficial fungal infections typically caused by
dermatophytes.Superficial fungal infections are widespread, with an
estimated worldwide prevalence of 20%–25%, and include tinea pedis (athlete’s
foot), tinea cruris (jock itch), and tinea corporis (ringworm), among othersTopical allylamine (terbinaf...
Indian Journal of Pharmacology: Published: May, 2019Dermatophytic infections are the
common fungal infections aggravated by hot and humid climate. Terbinafine and Itraconazole
are commonly used oral antifungal agents for the same. However, resistance to
these drugs is being seen increasingly when used in the conventional doses and
duration. In...
Principles of TherapyTopical AntifungalsTopical medications have better
pharmacokinetics than their systemic counterparts. Hence, the combination is
expected to have better mycological clearance than systemic and topical alone. The combination should be from
different groups for wide coverage and also to prevent the emergence of resistance.
Dru...
International Journal of Scientific Study (IJSS): May, 2020Superficial fungal infections are
caused by dermatophytes, non-dermatophytic molds, and commensal yeasts. According to published literature, the global prevalence rate of superficial
mycotic infection has been found to be 20–25%. The recent prevalence of
dermatophytosis in India ranges f...
Seborrheic dermatitis (SD) is a
chronic common inflammatory skin disease, affecting 1-3% of the adult
population which is a common chronic erythematous scaly eruption usually seen
in areas rich in sebaceous glands, the scalp, face, chest, back, and flexural
areas.Malassezia yeasts have been
implicated in the pathogenesis of this disease. Antif...
JAMA Dermatology: Published November, 2022Despite the widespread use of
nutritional supplements and dietary interventions for treating hair loss, the
safety and effectiveness of available products remain unclear.The aim
of the study is to evaluate and compile the findings of all dietary
and nutritional interventions for treatment of hair loss a...
Pityriasis versicolor (PV) also
known as tinea versicolor, which is chronic and superficial fungal skin disease
caused by Malassezia yeasts. A permanent cure may difficult to achieve and this
may explain the long-term nature of the disease. Consequently, a preventive
treatment regimen may help to prevent the recurrence of pityriasis versicolor....
