Coronavirus-treatment-updates

The U.S. Food and Drug Administration authorizes bamlanivimab and etesevimab, administered together, to include emergency use as post-exposure prophylaxis (prevention) for COVID-19 in adults and pediatric patients (12 years of age and older weighing at least 40 kg) who are at high risk for progression to severe COVID-19, including hospitalizat...
Novel Coronavirus (COVID-19) Guidelines of Bangladesh. The guidelines for the diagnosis, treatment, and control of the coronavirus disease (COVID-19).
The U.S. Food and Drug Administration issued an emergency use authorization (EUA) for bamlanivimab and etesevimab administered together for the treatment of mild to moderate COVID-19. In a clinical trial of patients with COVID-19 at high risk for disease progression, a single intravenous infusion of bamlanivimab and etesevimab administe...
The Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA) has recommended adding sinus bradycardia to the product label for remdesivir as an adverse reaction of "unknown frequency."As part of its review, the committee examined all the available data on "rare" reported cases of bradycardia in patients, who re...
Ivermectin is an antiparasitic drug that is approved by the Food and Drug Administration (FDA) for the treatment of onchocerciasis and strongyloidiasis. Ivermectin is not FDA-approved for the treatment of any viral infection. In general, the drug is well tolerated. It is currently being evaluated as a potential treatment for COVID-19. Iverm...
The COVID-19 Treatment Guidelines have been developed to inform clinicians how to care for patients with COVID-19. Because clinical information about the optimal management of COVID-19 is evolving quickly. The recommendations in these Guidelines are based on scientific evidence and expert opinion. Each recommendation includes two...
This guidance document is intended for clinicians caring for COVID-19 patients during all phases of their disease (i.e., screening to discharge).  This update has been expanded to meet the needs of front-line clinicians and promotes a multi-disciplinary approach to care for patients with COVID-19, including those with mild, moderate, severe, a...
In patients with severe or critical Coronavirus disease 2019 (COVID-19) manifestations, a thromboinflammatory syndrome, with diffuse microvascular thrombosis, is increasingly evident as the final step of pro-inflammatory cytokines storm. Actually, no proven effective therapies for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) i...
In a clinical trial of patients with COVID-19, monoclonal antibody were shown to reduce COVID-19-related hospitalization or emergency room visits in patients at high risk for disease progression within 28 days after treatment when compared to placebo. The safety and effectiveness of this investigational therapy for use in the treatment of C...
FDA Authorizes Monoclonal Antibody for Treatment of COVID-19. The U.S. FDA issued an emergency use authorization (EUA) for the investigational monoclonal antibody therapy for the treatment of mild-to-moderate COVID-19 in adult and pediatric patients.
Dexamethasone : the first life-saving drug for COVID-19 patients Clinical trials make it possible to evaluate whether a treatment improves outcomes. Developing a hypothesis, for example if treatment A is better than standard treatment B, clinical trials enable understanding of the role of an intervention in improving patient care. In the...
Baricitinib plus remdesivir was superior to remdesivir alone in reducing recovery time and accelerating improvement in clinical status among patients with Covid-19, notably among those receiving high-flow oxygen or noninvasive ventilation. The combination was associated with fewer serious adverse events.