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Vaccine Journal: Published: February, 2024A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals.This study aimed to evaluate the risk of adverse events (13 medical conditions) of special interest (AESI) following COVID-19 vaccination from 10 sites across 8 countries. Most vaccine recipients were in...
The World Health Organization (WHO) classified the sub-variant of the Omicron strain JN.1 as a "variant of interest",because of "its rapidly increasing spread".JN.1 has been found in many countries around the world, including India, China, UK and the United States.TAKE HOME MESSAGEIt is descended from the BA.2.86 (Pirola) variant.It appears able...
Clinical Neurophysiology: April 2023Long term symptoms following COVID-19 (Long COVID) now affects a large number of patients with estimates of up to 100 million people world-wide.Prolonged “long-COVID” (P-L–COVID), seen several months after even a mild COVID-19 infection, is characterized by a complexity of neuromuscular, musculoskeletal, and...
Omicron subvariant XBB.1.16, the strain was first identified in January and has been monitored by the World Health Organisation (WHO) since 22 March, which upgraded it to a “variant of interest” in mid-April.Cases of Omicron variant XBB are mounting in China, forming a new wave expected to crest around 65 million cases...
JAMA: The Journal of the American Medical Association: Published on November, 2022Despite advances in treatment of COVID-19, additional therapies are needed, particularly in the outpatient setting. Novel oral antivirals have been authorized for high-risk individuals. Numerous repurposed drugs have been investigated for COVID-19.Ivermectin, an a...
The Journal of Dermatology: June, 2022Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared a pandemic by the World Health Organization, and COVID-19 continues to have a major impact on society. Numerous studies have reported impaired health sequelae after COVID-19 recovery, one...
JAMA Network: November, 2022After the worldwide outbreak leading to millions of acute cases and thousands of deaths, another important development is the occurrence or persistence of symptoms after the acute phase of SARS-CoV-2 infection (ie, long COVID or post–COVID-19).More than 100 post–COVID-19 symptoms affecting multiple systems (eg, cardi...
The persistence, severity, and disability associated with post-COVID conditions, often referred to as "long COVID," pose significant diagnostic and management challenges. Some patients who have been infected with SARS-CoV-2, the virus that causes COVID-19, have new, recurring, or ongoing symptoms and clinical findings four or more weeks after infec...
NICE guidelines: The holistic assessment, investigation, and management approach suggested by NICE are outlined here.Pulmonary Symptoms ManagementInvestigations:Pulmonary symptoms are common during long covid. NICE recommends that breathlessness may be investigated using an exercise tolerance test suited to the person’s ability, for example the one...
Coronavirus disease 2019 (COVID-19) is one of the most significant pandemics in human history caused by the virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 has infected >530 million people, of which >6.3 million have died since June 23, 2022. Recent research has indicated that COVID-19 might be a risk fa...
Neurology (American Academy of Neurology) Journal: Published on March, 2022Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause long-term disability (long COVID) with new neurologic manifestations after even mild infections. Reports of peripheral neuropathy include Guillain-Barré syndrome, mononeuritis multiplex, brachial ple...
Obstetrics and Gynecology Journal: Published in September, 2022Vaccination against coronavirus disease 2019 is safe and effective at preventing illness, including hospitalization and death due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, and booster and additional primary dose COVID-19 vaccinations increase protec...