To reduce the development of drug-resistant bacteria and maintain the effectiveness of antibiotics and other antibacterial drugs, antibiotics should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should b...

Therapeutic indicationsAmoxicillin, alone or in combination with clavulanic acid, still accounts among the most widely used antibacterial agents. Although they are often considered 'twin drugs', they are different both in terms of antibacterial activities and of safety profile.Amoxicillin/clavulanate potassium is indicated in the treatment of i...

Published in JAMA: The Journal of the American Medical AssociationThis full article is available on the publisher's site-https://jamanetwork.com/journals/jama/fullarticle/2768929Expert comment By David Rakel MD, FAAFP Esther Millard Endowed Professor, University of Wisconsin School of Medicine & Public Health; Chair, Department of Family Medicin...