Featured
Best Practice Advice from the
American College of Physicians
The American
College of Physicians (ACP) and the Centers for Disease Control and Prevention
have recognized antibiotic-resistant infections as a global threat.
Antimicrobial overuse, particularly with broad-spectrum antibiotics, drives
resistance and causes adverse events in u...
Cefuroxime is a 2nd generation cephalosporin
group of broad-spectrum β-lactam antibiotics.Clavulanic acid is a beta lactamase inhibitor
used to enhance the effectiveness of beta lactam antibiotics. Clavulanic acid
does have some degree of bacterial activity; its principal role is as a
beta-lactamase inhibitor. Used in combination with the beta-...
JAMA: The Journal of the American Medical Association: October,
2023Cefepime and
piperacillin-tazobactam are commonly administered to hospitalized adults for
empirical treatment of infection. Although piperacillin-tazobactam has been
hypothesized to cause acute kidney injury and cefepime has been hypothesized to
cause neurological dysfunction,...
BMJ Journals: Gut: Published on March, 2023Inflammatory bowel disease (IBD) is
a chronic immune-mediated disease of the bowel, comprising two main subtypes:
Crohn’s disease (CD) and ulcerative colitis (UC).There is an increasing incidence of
inflammatory bowel disease (IBD) for which environmental factors is suspected.
Antibiotics have been ass...
From The Journal of Infectious Diseases and
The British Medical Journal:
Sepsis mortality has improved
following advancements in early recognition and standardized management, including
emphasis on early administration of appropriate antimicrobials. However,
guidance regarding antimicrobial duration in sepsis is surprisingly limited....
The use of empiric antibiotic therapy
appears to prevent neither deterioration nor death among patients with COVID-19
pneumonia, as shown in this study.
Take Home Message
In a group of patients with
COVID-19 pneumonia, antibiotics were commonly started in those who were
severely ill. Patients who did vs did not receive antibiotics mor...
JAMA Surgery:
Surgical
site infections (SSIs) are infections of the incision or organ or space that
occur after surgery. Surgical patients initially seen with more
complex comorbidities and the emergence of antimicrobial-resistant pathogens
increase the cost and challenge of treating SSIs. The prevention of SSI is
increasingly important...
International Journal of Dentistry:
Odontogenic infections are one of
the most prevalent diseases worldwide and the principal reason for seeking
dental care. Dental prescriptions account for nearly 7% to 11% of all common
antibiotic prescriptions.
The commonest emergency odontogenic
infections are periapical abscess (25%), pericoron...
Cesareans
delivery is the most common risk factor for postpartum maternal infections,
which occurs at a rate of 18%–38%. Factors that have been associated with an
increased risk of infection among women who have a cesarean delivery include
emergency cesarean section, labor and its duration, ruptured membranes and the
duration of rupture, t...
Community-acquired pneumonia (CAP)
is a significant cause of respiratory morbidity and mortality in children,
especially in developing countries. Worldwide, CAP is the leading cause of
death in children younger than five years.
Clinical assessment requires
careful evaluation of clinical features, severity, and evidence of
complications....
Cefuroxime is a 2nd generation cephalosporin group of broad-spectrum β-lactam
antibiotic.Clavulanic acid is a
beta lactamase inhibitor used to enhance the effectiveness of beta lactam
antibiotics.Cefuroxime and Clavulanic Acid: A
combination of cefuroxime and ß -lactamase inhibitor (Clavulanic acid) for the
treatment of various bacterial infec...
Signs and symptoms
Dysuria
Urinary urgency and frequency
A sensation of bladder fullness or lower abdominal
discomfort
Suprapubic tenderness
Flank pain and costovertebral angle tenderness (may
be present in cystitis but suggest upper UTI)
·
Cloudy
urine with an unpleasant
odour
Fevers, chills, vomiting and mal...
