First COVID -19 antiviral oral drug

Britain authorizes Merck’s Molnupiravir, the world’s first approval of oral covid-19 treatment pill. The drug is waiting for FDA review and approval.

Britain became the first country in the world to approve a potentially game-changing Covid-19 antiviral pill jointly developed by US drugmaker Merck and Ridgeback Biotherapeutics, in a boost to the fight against the pandemic.

A study of molnupiravir slashed the risk of hospitalization or death by 50% when given to nonhospitalized adult patients who tested positive for COVID-19, according to Merck.

Who to prescribe?

Britain's Medicines and Healthcare products Regulatory Agency (MHRA) recommended the drug: 

Molnupiravir, for treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults with a positive SARS-COV-2 diagnostic test and who have at least ONE risk factor for developing severe illness. Such risk factors include obesity, older age (>60 years), diabetes mellitus, or heart disease.

How to prescribe?

The Medicines and Healthcare products Regulatory Agency (MHRA) recommended the drug, molnupiravir 800 mg (four 200 mg capsules) taken orally, to be used as soon as possible following a positive Covid-19 test twice a day for 5 days, starting within 5 days of the onset of symptoms.

The Directorate General of Drug Administration (DGDA) of Bangladesh has granted some local pharmaceutical companies approval for the production and marketing of molnupiravir, the first-ever Covid-19 pill.

Covid-19 pills are no substitute for vaccines and will not prevent the Coronavirus disease.


Source

https://www.gov.uk/government/news/first-oral-antiviral-for-covid-19-lagevrio-molnupiravir-approved-by-mhra   

https://www.reuters.com/business/healthcare-pharmaceuticals/britain-approves-mercks-oral-covid-19-pill-2021-11-04/ 

https://www.washingtonpost.com/health/2021/11/04/covid19-pill-merck-molnupiravir-approval-uk/ 

https://www.dhakatribune.com/bangladesh/2021/11/09/dgda-clears-beximco-pharma-to-produce-merck-s-covid-pills

 

Note: For informational purposes only. Consult your textbook for advising your patients.


This is for informational purposes only. You should consult your clinical textbook for advising your patients.