A new draft recommendation relating to anticoagulation for discharged patients with COVID-19 has been issued by the American Society of Hematology (ASH).

For patients with COVID-19 who are being discharged from the hospital and who do not have suspected or confirmed venous thromboembolism or another indication for anticoagulation, the ASH guideline panel suggests not using anticoagulant outpatient thromboprophylaxis (conditional recommendation based on very low-certainty evidence).

When deciding whether to use post discharge thromboprophylaxis, an individualized assessment of the patient's risk for thrombosis and bleeding and shared decision-making are important. There are no validated risk assessment models for estimating thrombotic and bleeding risk for COVID-19 patients after discharge.

For patients judged to be at high thrombotic risk and low bleeding risk, the panel acknowledges that post discharge thromboprophylaxis may be reasonable.

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