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Gastroenterology: AGA Journal: Published March, 2019Prior research has shown an association between proton pump inhibitors and fracture risk. This study checked for markers for bone reabsorption and formation and followed bone mineral density and the incidence of fractures. It also looked at levels of calcium, magnesium, phosphorous, and parath...
During the holy month of Ramadan, Muslims practice daily fasting from dawn to sunset. This commitment changes their daily food routine in terms of number of meals, quantity of caloric intake, and types of food consumed. This change in consumption patterns during Ramadan has an effect on metabolism and weight, sleeping patterns, and possibly ga...
Neurogastroenterology and Motility Journal: Published: September 2022GERD is a condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications. These symptoms include typical ones, such as heartburn, regurgitation, or both, angina-mimicking non-cardiac chest pain, and extra-esophageal symptoms,...
Gastro-esophageal reflux disease (GERD) is a disorder involving troublesome symptoms associated with persistent reflux of gastric contents into the esophagus. Symptoms include heartburn, cough, epigastric pain, vomiting, and regurgitation.GERD is proposed to have 5 distinct presentations—nonerosive GERD (NERD), erosive esophagitis (EE), functio...
Dexlansoprazole is a new proton pump inhibitor (PPI) with a dual delayed-release system. Both dexlansoprazole and esomeprazole are an enantiomer of lansoprazole and omeprazole respectively.TAKE HOME MESSAGEThis study aims to compare the efficacy of Dexlansoprazole with Esomeprazole in healing erosive oesophagitis (EO), the maintenance of healed...
International Journal of Molecular Science: Published on January 2024Gastroesophageal reflux disease (GERD) is a common disease of the digestive system with a worldwide prevalence of 8 to 33% and is characterized by the persistent reflux of gastroduodenal content that ascends through the esophageal tube, causing esophageal and extraesophageal...
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibroinflammatory lung disease associated with increased morbidity and mortality. As its name suggests, the exact cause of the disease is not known. However, some genetic and environmental factors have been observed concurrently with the condition and are considered potential etiolo...
The American Journal of Gastroenterology GERD MEDICAL MANAGEMENT Management of GERD requires a multifaceted approach, taking into account the symptom presentation, endoscopic findings, and likely physiological abnormalities. Medical management includes lifestyle modifications and pharmacologic therapy, principally with medication...
Gastroesophageal reflux disease (GERD) continues to be among the most common diseases seen by gastroenterologists, surgeons, and primary care physicians. The American College of Gastroenterology (ACG) recently released an updated guideline on diagnosis and management of GERD which was published by the American Journal of Gastroenterology. In t...
Gastroesophageal reflux disease (GERD) and idiopathic pulmonary fibrosis (IPF) are two pathological conditions often strictly related, even if a clear relationship of causality has not been demonstrated. GERD is a frequent comorbidity in IPF patients, as demonstrated using combined multichannel intraluminal impedance-pH, despite being...
Proton Pump Inhibitors (PPIs) are widely considered the mainstay of medical treatment for GERD. Multiple publications have raised questions about adverse events, raising doubts about the safety of long-term use and increasing concern about overprescribing of PPIs. This guideline provides updated, evidence-based recommendations and practical...
Indian Journal of Gastroenterology: Published: 30 June 2022 TAKE HOME MESSAGE: Nocturnal acid breakthrough (NAB) may differ based on duration of proton pump inhibitor (PPI) action and Helicobacter pylori (H. pylori) infection; NAB may influence esophageal acidification (EA) and mucosal damage. Dexlansoprazole, a long-acting PPI,...