Story-of-the-week
Frontiers in Endocrinology: Published on March 2021Hypothyroidism is a common
condition caused by thyroid hormone deficiency. The prevalence of hypothyroidism
increases with age and subclinical hypothyroidism affects up to 15% of adults
65 years of age or older.Levothyroxine (L-T4) treatment of
overt hypothyroidism can be more challenging...
WHAT IS ASD AND HOW IS IT DEFINED
IN THE DSM-5?Autism spectrum disorder (ASD) is a
neurodevelopmental disorder with onset in early childhood that is associated
with a wide range of symptoms and ability levels. As defined by the Diagnostic
and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), Autism
Spectrum Disorder is a complex n...
JAMA Network: November, 2022After the worldwide outbreak
leading to millions of acute cases and thousands of deaths, another important
development is the occurrence or persistence of symptoms after the acute phase
of SARS-CoV-2 infection (ie, long COVID or post–COVID-19).More than 100 post–COVID-19
symptoms affecting multiple systems (eg, cardi...
BMJ Journals: Gut: Published on March, 2023Inflammatory bowel disease (IBD) is
a chronic immune-mediated disease of the bowel, comprising two main subtypes:
Crohn’s disease (CD) and ulcerative colitis (UC).There is an increasing incidence of
inflammatory bowel disease (IBD) for which environmental factors is suspected.
Antibiotics have been ass...
ACP Journals: Annals of Internal Medicine: Published
on February 2023In this systematic review and
meta-analysis, the authors assessed whether vitamin D administration decreases
the risk for diabetes in individuals with prediabetes. TAKE-HOME MESSAGECombining data from three
randomized trials, the authors demonstrated that vitamin D reduced the...
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BMJ: British Medical
Journal: Published on September, 2022The harmful effects of added sugars on various health
outcomes including cardiometabolic disorders have been extensively studied,
meta-analysed and are currently recognised as major risk factors by public
health authorities. In particular, the World Health Organization recommends
t...
Efficacy of Montelukast in preventing seasonal recurrence of vernal keratoconjunctivitis in Children
TAKE-HOME MESSAGEVernal keratoconjunctivitis is a
chronic, seasonally exacerbated, allergic inflammation of the eye.This prospective study evaluated
the efficacy and safety of montelukast in conjunction with typical topical
therapies for treating pediatric vernal keratoconjunctivitis (VKC). Patients
were evaluated for subjective improvement in...
Journal of the American Heart Association: published
on Jun 2022
COVID‐19 is an infectious illness,
with an increased risk of thromboembolism. The overall rate of venous
thromboembolism and arterial thromboembolism among patients with COVID‐19 is
21% and 2%, respectively.
Therefore, this complication
represents an important therapeut...
The British Medical Journal (BMJ): Published 17 May 2022
Compared with vaginal delivery,
caesarean section carries a substantially increased risk of maternal postpartum
infections. This risk can be reduced by routine provision of prophylactic
antibiotics.
Evidence from randomized controlled
trials shows that antibiotics are more effe...
Paracetamol has often been cited as
a safer alternative to non-steroidal anti-inflammatory drugs (NSAIDs) with
regards blood pressure and cardiovascular health. But now researchers have
raised concerns about this, suggesting that those taking paracetamol long-term
may be at greater risk of heart attack and stroke.Long-term paracetamol use could...
The rapidly escalating coronavirus
disease 2019 (COVID-19) pandemic has focused attention on the diagnosis and
treatment of patients with acute respiratory infection in an unprecedented
manner. Although most of the lung injury patients have is believed to be caused
by the virus, concern over bacterial co-infection also informs current
treatmen...
