Drugs-for-gerd
A Systematic Review and
Meta-analysisGastroesophageal reflux disease (GERD) is a chronic digestive
disorder resulting from the reflux of gastric contents into the esophagus that
is often accompanied by troublesome symptoms of heartburn, acid regurgitation,
or other extra-esophageal symptoms such as chest pain, chronic cough,
hoarseness or glob...
The American Journal of
Gastroenterology
Gastroesophageal
reflux disease (GERD) continues to be among the most common diseases seen by
gastroenterologists, surgeons, and primary care physicians.
GERD is
the condition in which the reflux of gastric contents into the esophagus
results in symptoms and/or complications. GERD is defined b...
Clinical Gastroenterology and Hepatology
TAKE-HOME MESSAGE
This review presents best practice
advice statements to help healthcare providers in the treatment of patients
with gastroesophageal reflux disease (GERD).
To optimize care and response,
diagnostic testing should be personalized and management should be tailored to
the ind...
Proton
pump inhibitors (PPIs) are among the most commonly used medications in the
world. Developed for the treatment and prevention of acid-mediated upper
gastrointestinal conditions, these agents are being used increasingly for
indications where their benefits are less certain.
PPI over prescription
imposes an economic cost and contri...
Key Information
In the last decade, gastro-esophageal
reflux disease (GERD) and its complications of Barrett's oesophagus and
oesophageal adenocarcinoma are increasingly prevalent, especially in Asia. The
rise in GERD among Asians is largely attributed to a recent increase in the
prevalence of obesity.
Physiological dysfunction of the...
BioMed Central (BMC) Gastroenterology Journal:
Gastroesophageal
reflux disease (GERD) is one the most common medical complaints in
pregnant women. Its prevalence has been reported to reach as high as 80% in
certain populations. The prevalence of GERD is also increased as pregnancy
progresses from the first to third trimester. Some women...
Heartburn is a cardinal symptom of gastro-oesophageal reflux disease
(GERD) and is among the most common patient complaints encountered by physicians.
TAKE HOME MESSAGE:
This study compared the effect of Antacid & Alginate Liquid to an antacid
in controlling post-prandial acid reflux in GERD patients.
The current investigation demons...
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The authors of this meta-analysis evaluated the
efficacy of alginate-containing compounds for the treatment of
gastroesophageal reflux disease (GERD) symptoms. The odds of resolution of
GERD symptoms was significantly greater with alginate-based therapies than
with placebo or antacids. Alginate therap...
The management of gastroesophageal
reflux disease (GERD) has been revolutionized with the development of proton
pump inhibitors (PPIs). Unfortunately, due to the inherent pharmacokinetic and
pharmacodynamic profiles of conventional PPIs, many patients continue to suffer
from symptoms related to GERD despite appropriate use of PPIs.
Curr...
The American Journal of GastroenterologyTAKE-HOME MESSAGE
In a study evaluating sleep position and nocturnal
gastroesophageal reflux, the sleep positions of 57 individuals referred
for ambulatory pH impedance were measured and analyzed. The left lateral
position was associated with significantly shorter acid exposure time than...
Reflux disease is a chronic and
progressive condition. Treatment options depend on the disease stage. The
disease stage is determined by the severity of reflux into the esophagus. This
in turns depends on how frequent and how long are the reflux episodes. GERD is also associated with a
spectrum of symptoms that ranges from mild heartburn to sev...
Many women experience heartburn
during pregnancy. It can be extremely uncomfortable and can negatively affect
women’s experience of pregnancy and their quality of life.Dietary changes may help to
reduce or stop heartburn. The NICE guideline on gastrooesophageal reflux
disease and dyspepsia in adults includes recommendations about dietary and
l...
