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Antibiotic resistance is one of the greatest public health challenges of our time—few treatment options exist for people infected with antibiotic-resistant bacteria.
The Infectious Diseases Society of America (IDSA) and American Thoracic Society (ATS) issued updated clinical practice guidelines for community-acquired pneumonia (CAP).Community-acquired pneumonia (CAP), an infection of the lung parenchyma that occurs in persons outside of a hospital setting, is associated with high morbidity and mortality.&nb...
Best Practice Advice from the American College of Physicians The American College of Physicians (ACP) and the Centers for Disease Control and Prevention have recognized antibiotic-resistant infections as a global threat. Antimicrobial overuse, particularly with broad-spectrum antibiotics, drives resistance and causes adverse events in u...
JAMA: The Journal of the American Medical Association: October, 2023Cefepime and piperacillin-tazobactam are commonly administered to hospitalized adults for empirical treatment of infection. Although piperacillin-tazobactam has been hypothesized to cause acute kidney injury and cefepime has been hypothesized to cause neurological dysfunction,...
eClinicalMedicine Journal: The LANCET: Published on December, 2022Gram-negative bacteremia is common in both community and health care settings, with a significant increase in incidence described for some Gram-negative bacteria in recent years.Prolonged duration of antibiotic therapy for such common infections may lead to increased resistance em...
From The Journal of Infectious Diseases and The British Medical Journal: Sepsis mortality has improved following advancements in early recognition and standardized management, including emphasis on early administration of appropriate antimicrobials. However, guidance regarding antimicrobial duration in sepsis is surprisingly limited....
Journal of Oral and Maxillofacial Surgery: Odontogenic infections are a common problem in dentistry, and their treatment often requires the use of antibiotics besides the removal of the source of infection, which frequently makes it more difficult for clinicians to make a decision regarding the choice of antibiotic. The pathogenesis...
JAMA Surgery: Surgical site infections (SSIs) are infections of the incision or organ or space that occur after surgery. Surgical patients initially seen with more complex comorbidities and the emergence of antimicrobial-resistant pathogens increase the cost and challenge of treating SSIs. The prevention of SSI is increasingly important...
International Journal of Dentistry: Odontogenic infections are one of the most prevalent diseases worldwide and the principal reason for seeking dental care. Dental prescriptions account for nearly 7% to 11% of all common antibiotic prescriptions. The commonest emergency odontogenic infections are periapical abscess (25%), pericoron...
Cesareans delivery is the most common risk factor for postpartum maternal infections, which occurs at a rate of 18%–38%. Factors that have been associated with an increased risk of infection among women who have a cesarean delivery include emergency cesarean section, labor and its duration, ruptured membranes and the duration of rupture, t...
Community-acquired pneumonia (CAP) is a significant cause of respiratory morbidity and mortality in children, especially in developing countries. Worldwide, CAP is the leading cause of death in children younger than five years. Clinical assessment requires careful evaluation of clinical features, severity, and evidence of complications....
The British Pharmacological Society Journal: Published: 05 September 2019 Penicillin’s are widely used during pregnancy for various bacterial infectious indications. Amoxicillin, rapidly crosses the placenta following absorption to the bloodstream, It is prescribed both as a sole medicine as well as in combination with clavulanic acid mos...