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JAMA Cardiology: Published on November, 2022TAKE-HOME MESSAGEQuestion:  Does vitamin D prevent statin-associated muscle symptoms and reduce statin discontinuation?This study assessed whether vitamin D supplementation (2000 IU of cholecalciferol) would prevent statin-associated muscle symptoms (SAMS) and reduce statin discontinuation in 2083 part...
Journal of the American College of Cardiology: Published on December, 2022Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified.The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifi...
ACP Journals: Annals of Internal Medicine: Published on February 2023In this systematic review and meta-analysis, the authors assessed whether vitamin D administration decreases the risk for diabetes in individuals with prediabetes. TAKE-HOME MESSAGECombining data from three randomized trials, the authors demonstrated that vitamin D reduced the...
The Journal of Laryngology & OtologyThyroidectomy is one of the most common interventions in general and endocrine surgery for patients with hyperthyroidism, goiter, thyroid nodules or thyroid cancer.Post-operative hypocalcaemia is a recognized complication of thyroid surgery. The most common cause of acute symptomatic hypocalcemia in hospitali...
Take Home Messages: Derangement in calcium homeostasis is common in nephrotic syndrome (NS). It is asuumed that low serum total calcium and vitamin D levels are due to loss of protein-bound calcium and vitamin D. But it is unclear if free calcium and free vitamin D levels are truly low. The guideline is lacking with regards to calci...
JAMA: The Journal of the American Medical Association: Published June 21, 2022 Cardiovascular disease and cancer are the 2 leading causes of death. Vitamin and mineral supplementation has been proposed as a preventive strategy for both diseases because of shared disease pathways involving oxidative stress, inflammation, and methionine m...
Journal of the American College of Cardiology (JACC): Published on Feb 2021 Calcium and Vitamin D supplements are commonly used, often together, to optimize bone health. Multiple observational studies have linked low serum 25-hydroxyvitamin D concentrations with increased cardiovascular risk. Given their widespread availability, lo...
Autoimmune diseases, characterized by an inflammatory autoimmune response to self-tissues, are the third leading cause of morbidity in the industrialized world and a leading cause of mortality among women. Autoimmune diseases (including rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease, and psoriasis) are chronic conditio...
Worldwide, cardiovascular diseases (CVDs) Source are one of the leading causes of death. Every year, an estimated 17.9 million people around the world die as a result of complications from heart diseases. For context, this means that CVDs are responsible for 32% of all deaths globally.Prior studies Source show that various factors — such as se...
Calcium and vitamin D supplements needs for prevention of osteoporosis and osteoporotic fractures. There is evidence of significant benefit in people at risk of deficiency.For individuals who cannot get enough calcium through their diets, supplements may be beneficial. These should be limited to 500-600 mg per day and it is generally recommende...
Vitamin D deficiency is one of the most prevalent micronutrient deficiencies in the world. It has emerged as a public health problem in many developing countries of the world including Bangladesh. Over a billion people worldwide are vitamin D deficient. The worldwide prevalence of vitamin D deficiency is 30-50% among children and even higher in...
Vitamin D is known for its role in calcium homeostasis for optimal skeletal health. It was previously believed that only elderly or hospitalized patients were at risk for vitamin D insufficiency, but many people in the general population have insufficient levels of Vitamin D (25-hydroxyvitamin D or in short, 25[OH]D).We review the role of vita...