PubMed: September 2023Seizures are common in neonates, but there is substantial management variability. The Neonatal Task Force of the International League Against Epilepsy (ILAE) developed evidence-based recommendations about antiseizure medication (ASM) management in neonates in accordance with ILAE standards. Seizures are the most common neu...

Seizures are the most common manifestation of neurological insult during the neonatal period. The most common cause of symptomatic neonatal seizures is hypoxic/ischemic encephalopathy (HIE) which affects approximately 1-2/100 live births.There are no evidence-based guidelines for the pharmacologic treatment of neonatal seizures and management...

American Epilepsy Society issues guideline and treatment algorithm for convulsive status epilepticus. The guideline was endorsed by the Epilepsy Foundation, Child Neurology Society, and American College of Emergency Physicians.Status epilepticus – continuous or rapid sequential seizure activity for 30 minutes or more – is a medical emergency wi...

JAMA: The Journal of the American Medical Association: Published on April 5, 2022 Epilepsy affects approximately 65 million people worldwide. Persistent seizures are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) over 12-month follow-up. The primary goal of epilepsy treatment is to eliminate seiz...

The New England Journal of Medicine (NEJM): Published on July 15, 2021 The incidence rate of a single unprovoked seizure among adults is 23 to 61 cases per 100,000 person-years. After a first unprovoked seizure, the overall risk of recurrence may be as high as 60%, and this risk is highest within the first 2 years. Epilepsy is...