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Autoimmune diseases, characterized by an inflammatory autoimmune response to self-tissues, are the third leading cause of morbidity in the industrialized world and a leading cause of mortality among women. Autoimmune diseases (including rheumatoid arthritis, polymyalgia rheumatica, autoimmune thyroid disease, and psoriasis) are chronic conditio...
The U.S. Food and Drug Administration authorized Pfizer’s Paxlovid (nirmatrelvir tablets and ritonavir tablets, co-packaged for oral use) for emergency use for the treatment of mild-to-moderate coronavirus disease in adults and children 12 years and older weighing at least 40 kilograms with positive results of direct SARS-CoV-2 testing, and who...
The U.S. Centers for Disease Control and Prevention announced that the recommended isolation time for people with COVID-19 is now reduced from 10 to 5 days for those who are asymptomatic. The agency said that people who test positive should isolate for 5 (five) days, and if they are asymptomatic, or their symptoms are resolving (without fe...
Worldwide, cardiovascular diseases (CVDs) Source are one of the leading causes of death. Every year, an estimated 17.9 million people around the world die as a result of complications from heart diseases. For context, this means that CVDs are responsible for 32% of all deaths globally.Prior studies Source show that various factors — such as se...
SummaryWhat is already known about this topic?Pregnant women with COVID-19 are at increased risk for severe illness and adverse birth outcomes, yet many remain reluctant to be vaccinated.What is added by this report?In a retrospective cohort of >40,000 pregnant women, COVID-19 vaccination during pregnancy was not associated with preterm bir...
Vitamin D deficiency is one of the most prevalent micronutrient deficiencies in the world. It has emerged as a public health problem in many developing countries of the world including Bangladesh. Over a billion people worldwide are vitamin D deficient. The worldwide prevalence of vitamin D deficiency is 30-50% among children and even higher in...
Vitamin D is known for its role in calcium homeostasis for optimal skeletal health. It was previously believed that only elderly or hospitalized patients were at risk for vitamin D insufficiency, but many people in the general population have insufficient levels of Vitamin D (25-hydroxyvitamin D or in short, 25[OH]D).We review the role of vita...
Key Points about Vitamin D Deficiency and Dependency Vitamin D deficiency is common and results from inadequate exposure to sunlight and inadequate dietary intake (usually occurring together) and/or from chronic kidney disease.   The deficiency can cause muscle aches and weakness, bone pain, and osteomalacia....
The following groups are at a particularly high risk of vitamin D deficiency:Infants and children aged 65 yearsIndividuals who have darker skin (e.g. people of South Asian ethnic origin).People who have no or limited sun exposure, including people who:  cover their skin for cultural reasons are confined in...
In adults, vitamin D deficiency is defined as a serum 25-hydroxyvitamin D level of less than 20 ng per mL (50 nmol per L), and vitamin D insufficiency is defined as a serum 25-hydroxyvitamin D level of 20 to 30 ng per mL (50 to 75 nmol per L). RemoveAvailable Brand
 Having a comprehensive understanding of the transmission patterns of SARS-CoV-2 is necessary for the successful implementation of these public health measures.For example, obtaining information about when individuals with SARS-CoV-2 are most likely to spread the virus may guide decisions about the duration of contact tracing an...