The Journal of Sexual Medicine: January 2020Premature ejaculation (PE) is a common sexual dysfunction; the available options for PE treatment remain unsatisfactory. Premature ejaculation (PE) is the most common form of male sexual dysfunction. Globally, between 20% and 40% of men, at some point in their lives, have reported complaint of PE.The...

The Journal of Urology:Clomipramine is a tricyclic antidepressant (TCA) that has been found effective at a daily dose of 25 mg or 50 mg for premature ejaculation (PE) in multiple studies. Additionally, TCAs can carry significant side effects such as dizziness, dry mouth, and constipation. As a result, on-demand treatment is greatly preferred, e...

Nature Reviews: Urology: Published on August, 2022Premature ejaculation (PE) is a prevalent and common male sexual dysfunction. The first treatment modalities for PE were with psychotherapy focussing on the sexual relationship and anxiety related to sexual satisfaction with a partner. The use of sexual psychology can play a role in the...