The Lancet: Published on November, 2022Aspirin is widely recommended for the secondary prevention of thrombotic vascular disease.  Its use is limited principally by increased risk of bleeding, particularly from the gastrointestinal tract.The risks of upper gastrointestinal bleeding can be mitigated in part by acid suppression with proton pump i...

Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency. In Western countries, its incidence was estimated to be over 100 cases per 100 000 adults per year. Fortunately, the mortality rates of AUGIB have decreased over the past few decades, largely attributable to improvements in endoscopic and pharmacological therapies...

American College of Gastroenterology (ACG 2021): Sequencing of Stool Samples technology eliminates need for endoscopic gastric biopsyHelicobacter pylori is a major human pathogen for which increasing antibiotic resistance constitutes a serious threat to human health. Antimicrobial resistance is an ever-growing problem for successful eradication...

Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI over prescription imposes an economic cost and contri...

TAKE-HOME MESSAGE The authors investigated physician adherence with recommending peptic ulcer disease (PUD) prophylaxis for elderly patients who were receiving dual antiplatelet therapy or anticoagulation or who were at risk of bleeding PUD, as per expert consensus guidelines from the American College of Gastroenterol...