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The association of Obesity and Dengue severity in hospitalized adult patients
Journal of Microbiology, Immunology and Infection: April 2023Of the four DENV serotypes (DENV-1 to DENV-4), DENV-2 and DENV-3 are frequently associated with severe secondary dengue infections.Obesity is commonly associated with numerous comorbidities and is a major health burden. According to WHO guidelines, the dengue patients who have underly...
2-Year Effects of Semaglutide in Adults with Overweight or Obesity
Nature Medicine: Published on November, 2022Obesity is a chronic, relapsing disease with a substantial morbidity, mortality, and healthcare burden. Drug interventions for the treatment of obesity provide a potential valuable adjunct to lifestyle interventions, which often achieve only limited weight loss that is difficult to maintain. Semagluti...
2-Year Effects of Semaglutide in Adults with Overweight or Obesity
Nature Medicine: Published on November, 2022Obesity is a chronic, relapsing disease with a substantial morbidity, mortality, and healthcare burden. Drug interventions for the treatment of obesity provide a potential valuable adjunct to lifestyle interventions, which often achieve only limited weight loss that is difficult to maintain. Semagluti...
AGA Clinical Practice Guideline on Pharmacological Interventions for Adults with Obesity
AGA Gastroenterology Journal: Published on November, 2022In adults, obesity-related complications, such as cardiovascular disease, stroke, type 2 diabetes mellitus (T2DM), nonalcoholic steatohepatitis, obstructive sleep apnea, osteoarthritis, and certain types of cancer (eg, colorectal cancer), have also increased, contributing to high morbidit...
Calorie Restriction With or Without Time-Restricted Eating in Weight Loss
The New England Journal of Medicine (NEJM): Obesity is a major global public health challenge. Weight loss by means of lifestyle modification has been documented to be the cornerstone of weight management. Daily calorie restriction is a well-established primary weight-loss strategy for obese patients. However, most trials of dietary...
Obesity is an independent risk factor for GERD
Gastroesophageal reflux disease (GERD) is a common condition, with multifactorial pathogenesis, affecting up to 40% of the population. Obesity is also common. Obesity and GERD are clearly related, both from a prevalence and causality association. GERD symptoms increase in severity when people gain weight. Obese patients tend to have more se...