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Annals of Internal Medicine: Published May 2024Testosterone (T) levels slowly decline as we age, and serum hormone-binding globulin (SHBG) levels gradually increase. As SHBG increases, there is less T available to the tissues. There are several conditions that reduce levels of T; these include being overweight, having metabolic dysfunction, liv...
Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with Systolic (SBP) and Diastolic Blood Pressure (DBP), and the risk of hypertension i...
Diabetes Care: May, 2023Type 2 diabetes is associated with increased risk of microvascular and macrovascular disease, with the risk of cardiovascular (CV) mortality more than double in people with type 2 diabetes compared with those without. In the last decade, large dedicated CV outcome trials in people with type 2 diabetes and at high risk or...
ADA: Diabetes Journals: Published June 2023Diabetes mellitus (DM) is one of the most important causes of CKD. Moreover, both DM and CKD are important risk factors for cardiovascular disease (CVD). Metformin is still the first-line drug for DM management. The concern, of course, is an increased risk of metformin-associated lactic acidosis (MALA)...
Journal of the American Heart Association (AHA): Published on November, 2022Sleep, alongside diet and physical activity (PA), is one of the 3 pillars of health, but unlike other health behaviors, healthy sleep is not included in the American College of Cardiology/American Heart Association (AHA) cardiovascular disease (CVD) prevention guideline...
Journal of the American College of Cardiology: Published on December, 2022Healthy dietary patterns are rich in micronutrients, but their influence on cardiovascular disease (CVD) risks has not been systematically quantified.The goal of this study was to provide a comprehensive and most up-to-date evidence-based map that systematically quantifi...
AHA Journal: Stroke: A Journal of Cerebral Circulation: Published on June, 2022Millions of women worldwide use exogenous hormones as oral contraceptives or hormone replacement therapy. Still, time-dependent and long-term consequences of exogenous hormones on stroke risk remains unclear.TAKE-HOME MESSAGEIn this UK Biobank analysis including 257,...
The Lancet: The traditional Mediterranean diet consisted of a high proportion of fruits, vegetables, nuts, legumes, and cereals, a moderate intake of fish and poultry as the main protein source and olive oil as the main fat source. A low intake of dairy products, red meat, processed meats, and sweets. Current recommendation for patient...
US Preventive Services Task Force Recommendation Statement (USPSTF): JAMA NETWORK: Published on August, 2022Cardiovascular disease (CVD) is highly prevalent and the leading cause of morbidity and mortality. Statins are used to prevent CVD-associated morbidity and mortality because of their positive effects on lipid profiles as well as anti-infl...
JAMA Network: Published on April, 2022CVD remains a leading cause of morbidity and mortality globally. Prevention strategies must address all aspects of a patient’s lifestyle habits, including healthy nutrition, physical activity, smoking cessation, and stress reduction. When an individual’s risk is sufficiently high, pharmacologic therapy is o...
BMJ: British Medical Journal: Published on September, 2022The harmful effects of added sugars on various health outcomes including cardiometabolic disorders have been extensively studied, meta-analysed and are currently recognised as major risk factors by public health authorities. In particular, the World Health Organization recommends t...