The American College of Obstetricians and Gynecologists (ACOG) has provided recommendations for the treatment of vasomotor and vaginal symptoms related to menopause.Vasomotor and vaginal symptoms are cardinal symptoms of menopause. Vasomotor symptoms can be particularly troubling to women and are the most commonly reported menopausal symptoms.M...

Hormone therapy is the most effective treatment for vasomotor symptoms (VMS) and other menopausal symptoms. Changing estrogen levels during menopause may impact multiple components involved in maintaining temperature homeostasis.Health care professionals should individualize therapy based on clinical factors and patient preference. They should...

Studies clarify menopausal HT’s impact on breast cancer riskOne of the greatest concerns of women who are considering Menopausal Hormone Therapy (MHT) is the relationship between hormone use and breast cancer. Data from the The Women’s Health Initiative (WHI) suggest an increase in risk with combined estrogen-progestin therapy, but a reduction i...

TAKE-HOME MESSAGE A case–control study examined the role of hormone replacement therapy (HRT) in postmenopausal women, including 30 women on HRT and 30 controls, in terms of salivary estrogen and mouth dryness symptoms.   After 6 months, HRT appeared to restore levels of salivary estrogen as well as reduce mouth dr...

TAKE-HOME MESSAGE Menopausal hormone therapy has been associated with various malignancies. In this Swedish registry study, the authors investigated the use of menopausal hormone therapy and risk of colorectal cancer.    The study found that Menopausal hormone therapy was associated with overall reduced odds for co...

Conjugated estrogens/bazedoxifene is a selective estrogen receptor modulator. Bazedoxifene stimulates estrogen receptors in bone and has antagonistic effects in the breast and uterus. Conjugated estrogens/bazedoxifene is labeled for the treatment of moderate to severe vasomotor symptoms associated with menopause and prevention of postmenopausal...