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The Journal of Laryngology & OtologyThyroidectomy is one of the most common interventions in general and endocrine surgery for patients with hyperthyroidism, goiter, thyroid nodules or thyroid cancer.Post-operative hypocalcaemia is a recognized complication of thyroid surgery. The most common cause of acute symptomatic hypocalcemia in hospitali...
Take Home Messages: Derangement in calcium homeostasis is common in nephrotic syndrome (NS). It is asuumed that low serum total calcium and vitamin D levels are due to loss of protein-bound calcium and vitamin D. But it is unclear if free calcium and free vitamin D levels are truly low. The guideline is lacking with regards to calci...
Journal of the American College of Nutrition: It is widely recognized that COVID-19 severity is a multifactorial condition; several risk factors have been identified, including advanced age, ethnicity, type 2 diabetes, hypertension, obesity, renal dysfunction, and cardiovascular diseases. Interestingly, each of these factors is also...
JAMA Network: A Systematic Review and Meta-analysis Osteoporosis is characterized by reduced bone mass and fragmentation of bone architecture, resulting in an increased risk of fracture. Approximately 1 in 2 women and 1 in 5 men aged 50 years or older will experience an osteoporotic fracture in their remaining lifetime. Hip fracture is...
The New England Journal of Medicine (NEJM): Obesity is a major global public health challenge. Weight loss by means of lifestyle modification has been documented to be the cornerstone of weight management. Daily calorie restriction is a well-established primary weight-loss strategy for obese patients. However, most trials of dietary...
JAMA: The Journal of the American Medical Association: Published June 21, 2022 Cardiovascular disease and cancer are the 2 leading causes of death. Vitamin and mineral supplementation has been proposed as a preventive strategy for both diseases because of shared disease pathways involving oxidative stress, inflammation, and methionine m...
Overview of OsteoporosisOsteoporosis is a disease characterized by low bone mass and deterioration of bone tissue and bone structure, which can lead to increased bone fragility and risk of fracture. The most common fractures associated with osteoporosis are in the hip, spine, wrist, and shoulder. Osteoporosis is the major cause o...
The role of CalciumCalcium is a key structural component of bone and is built into bone as a mineral complex that includes calcium and phosphate. Calcium is a major building-block of bone – the skeleton houses 99% of the body’s calcium stores. The calcium in bones also acts as a reservoir for maintaining calcium levels in the blood, which is n...
TAKE-HOME MESSAGE Patients who are hospitalized with COVID-19 have been shown to have a high risk of thromboembolic events post discharge. In this open-label randomized trial, the authors showed that, in high-risk patients who are hospitalized for COVID-19, the use of thromboprophylaxis and rivaroxaban for 35 days after di...
The U.S. Food and Drug Administration revised the emergency use authorization (EUA) of bamlanivimab and etesevimab monoclonal antibodies (previously authorized for pediatric patients 12 years of age and older weighing at least 40 kilograms, or about 88 pounds), to additionally authorize bamlanivimab and etesivimab administered together for the...
A nationwide Spanish cross-sectional study was conducted. Study included patients with cutaneous reactions within 21 days of any dose of the approved vaccines at the time of the study.Published in the British Journal of Dermatology Evaluation of 405 cutaneous reactions after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) va...
Genetic factors play a significant role in determining whether an individual is at increased risk of osteoporosis. However, lifestyle factors such as diet and physical activity also influence bone development in youth and the rate of bone loss later in life.Advice for adults: Ensuring a well-balanced diet and adequate calcium intake&nbs...