American College of Gastroenterology (ACG 2021): Sequencing of Stool Samples technology eliminates need for endoscopic gastric biopsyHelicobacter pylori is a major human pathogen for which increasing antibiotic resistance constitutes a serious threat to human health. Antimicrobial resistance is an ever-growing problem for successful eradication...

Proton pump inhibitors (PPIs) have been widely used for decades to treat acid-related diseases. PPIs exhibit a well-established safety profile and reduce gastric acid more effectively than histamine-2 receptor antagonists or antacids. However, observational studies suggest that long-term PPI therapy is associated with osteoporotic fract...

Peptic ulcer disease is often defined as a mucosal break greater than 3-5 mm in the stomach or duodenum with a visible depth. It is therefore an endoscopic diagnosis in contrast to dyspepsia, which is a clinical diagnosis based on symptoms alone. Peptic ulcer disease results from an imbalance between factors that protect the mucosa of the stoma...

Heartburn is a cardinal symptom of gastro-esophageal reflux disease (GERD) and is among the most common patient complaints.  Chronic GERD can cause heart burn, ulcers, scarring, and inflammation in the esophagus. It can also change cells that line the esophagus. This is known as Barrett's esophagus and it increases the risk of developi...