Posted by Incepta Pharmaceuticals Ltd.
JAMA Cardiology: Published on April, 2022TAKE-HOME MESSAGEQuestion: Is
low-dose triple combination antihypertensive therapy associated with greater
time at target blood pressure compared with usual care?Findings: This
secondary analysis of an open-label randomized controlled clinical trial
evaluated whether low-dose triple combination antihyp...
The LANCET: Diabetes &
Endocrinology: Published on July, 2022Diabetes is a major cause of death,
cardiovascular complications, and health-care burden worldwide.People with type 2 diabetes who
have high blood pressure are at an increased risk of morbidity and death from
major cardiovascular events.However, there are inadequate
randomised contro...
The New England Journal of Medicine (NEJM): Published
on April, 2022Antihypertensive treatment during
pregnancy reduces the frequency of severe hypertension (blood pressure,
≥160/110 mm Hg) but has not been shown to improve maternal, fetal, or neonatal
outcomes and has been associated with an increased risk of
small-for-gestational-age birth w...
The 2021 WHO hypertension guideline
aims to provide the most current and relevant evidence based global public
health guidance on the initiation of treatment (with pharmacological agents)
for hypertension in adults. The recommendations target adult,
non-pregnant patients who were appropriately diagnosed with hypertension and counseled
about li...
ACP Journals: Annals of Internal Medicine: Published on
November, 2022Current guidelines recommend using
direct oral anticoagulants (DOACs) over warfarin in patients with atrial
fibrillation (AF), but head-to-head trial data do not exist to guide the choice
of DOAC.The aim
of the study is to do a large-scale comparison between all DOACs
(apix...
The Lancet: Published on October, 2022Hypertension, or high blood
pressure, is a key risk factor for cardiovascular disease worldwide. Previous clinical trials supporting
the cardiovascular benefits of antihypertensive therapy primarily use
conventional morning dosing. Additionally, cardiovascular events
are temporally associated with the morni...
Journal of the American
Heart Association (AHA): Published on November, 2022Sleep, alongside diet and physical activity (PA), is one of
the 3 pillars of health, but unlike other health behaviors, healthy sleep is
not included in the American College of Cardiology/American Heart Association
(AHA) cardiovascular disease (CVD) prevention guideline...
JAMA Cardiology: Published on November, 2022TAKE-HOME MESSAGEQuestion: Does vitamin D prevent statin-associated muscle
symptoms and reduce statin discontinuation?This study assessed whether vitamin D supplementation (2000
IU of cholecalciferol) would prevent statin-associated muscle symptoms (SAMS)
and reduce statin discontinuation in 2083 part...
Hypertension is one of the leading
public health challenges worldwide. It is common in both developed and
developing countries.
Essential hypertension is believed
to be a result of complex interaction of genetic and environmental factors.
Increased peripheral resistance is responsible for most of the cases of
essential hypertension....
Hypertension is considered a major
health problem around the world. It’s associated with increasing risk of
mortality due to its complication which has a great impact on patient’s life
quality.
Chronic uncontrolled hypertension
is a significant risk factor for cardiovascular mortality and morbidity,
strokes, heart failure, and renal fai...
American Diabetes Association (ADA)
Professional Practice Committee: Recommendations
Treatment Strategies
Lifestyle Intervention:
Recommendation
For patients with blood pressure
>120/80 mmHg, lifestyle intervention consists of weight loss when
indicated, a Dietary Approaches to Stop Hypertension (DASH)-style eating
pattern inclu...
The American Diabetes Association
(ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current
clinical practice recommendations and is intended to provide the components of
diabetes care, general treatment goals and guidelines, and tools to evaluate
quality of care.
Atherosclerotic cardiovascular
disease (ASCVD)—defined as...