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The vaccine, known as mRNA-1273, was co-developed by the Cambridge, Massachusetts-based American biotechnology company Moderna, Inc., and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The trial, which will be conducted at U.S. clinical research sites, is expecte...
Background: The Oxford Vaccine Group at the University of Oxford are developing a new vaccine candidate for COVID-19, a chimpanzee adenovirus vaccine vector called AZD1222 (previously ChAdOx1). The team has previously developed a MERS vaccine. In India, the candidate is being jointly developed by the Serum Institute of India...
A diagram showing how the Oxford COVID-19 vaccine works. A chimpanzee adenovirus is used in the ChAdOx1 viral vector, engineered to match the SARS-CoV-2 spike protein.   The University of Oxford vaccine is delivered via a chimpanzee virus, called the vaccine vector. The vector contains the genetic code of t...
A vaccine in development by the British-Swedish company AstraZeneca and the University of Oxford is based on a chimpanzee adenovirus called ChAdOx1. Their Phase 1/2 trial revealed that the vaccine was safe, causing no severe side effects. It raised antibodies against the coronavirus as well as other immune defenses....
Background: CoronaVac (formerly PiCoVacc) is a formalin-inactivated and alum-adjuvanted candidate vaccine. Results from animal studies showed “partial or complete protection in macaques” exposed to SARS-CoV-2, according to a paper published by researchers in the journal Science.   Study Design: A Phase 1/2 trial enroll...
Chinese company Sinovac is developing a vaccine based on inactivated Covid-19 particles. The vaccine has shown a promising safety profile in the early stages of testing and is now moving into Phase 3 trials in Brazil involving 9,000 volunteers. Already Phase 3 trials for Sinovac's CoronaVac began last week in Indonesia involving...
There is an assertion that the Sinovac vaccine uses the "outdated" technology of inactivated whole viruses, and that such "next generation" technologies as mRNA vaccines (NIH/Moderna) and live adenovirus vaccines into which Covid genes are introduced (Oxford/Astra Zeneca) are preferable. There is no scientific basis for this...
An effective vaccine against SARS-CoV-2 will save countless lives in Bangladesh and around the world. If the Phase III trial of the Sinovac vaccine in Bangladesh demonstrates the vaccine to be safe and protective, Sinovac has agreed to provide over 110,000 free vaccine doses for the nation. And more importantly, Sinovac has...
The Bangladesh Medical Research Council or BMRC approved the phase 3 trial of Sinovac's vaccine candidate, known as CoronaVac.   But due to the novelty of the process, health authorities are awaiting approval from the government's top brass before flagging off the trials.   The International Centre for...
92 low- and middle-income economies eligible to get access to COVID-19 vaccines through Gavi COVAX Advance Market Commitment (AMC). A new landmark collaboration between Serum Institute of India (SII). the world’s largest vaccine manufacturer by volume, Gavi and the Bill & Melinda Gates Foundation will accelerate the manufacture...
A COVID‑19 vaccine is a biotechnology product intended to provide acquired immunity against coronavirus disease 2019 (COVID‑19). Researchers around the world are racing to develop a vaccine against Covid-19, with more than 170 candidate vaccines now tracked by the World Health Organization (WHO). RemoveSponsored contentHow Vacci...