PubMed Central: IntroductionThreatened miscarriage is a common disease during early pregnancy, with a morbidity of 30% to 40%, which could develop into a complete miscarriage or dystocia without timely treatment. Many pathogenic factors contribute to the threatened miscarriage, of which lacking progestogens due to the endocrine dysfunction of...

Key Information: Progesterone is essential for the maintenance of a healthy pregnancy. Progesterone is frequently prescribed to patients presenting with per vaginal (PV) bleeding in early pregnancy and a history of recurrent pregnancy loss. Any defect in the secretion of human chorionic gonadotropin or progesterone is associated with...

The British Medical Journal (BMJ): Increasing evidence suggests that reproductive factors unique to women are associated with a greater risk of death from non-communicable diseases. Even if reproductive events do not increase the risk of death from non-communicable diseases, they could be useful as an early stress test of underlying risk...

Successful oocyte implantation and a favorable pregnancy outcome rely on optimal progesterone levels. Therefore, progesterone deficiencies associated with infertility and miscarriages have commonly been treated with progestogens that mimic the activity of progesterone. Among those is dydrogesterone, an oral retrosteroid with a structur...

Threatened miscarriage is the most common complication in the first half of pregnancy affecting 20-25% of women. Diagnosis of threatened miscarriage is established when there is a viable pregnancy with vaginal bleeding and a closed cervix. Any woman who presents with threatened miscarriage; ultrasound imaging is performed to ascertain th...