Montelukast is used to control and prevent symptoms caused by asthma. It is also used before exercise to prevent breathing problems during exercise (bronchospasm).
Asthma Symptoms:
Montelukast recommended dose is once a day in the evening and it’s important to take it regularly even when patient have no symptoms.
Note: Montelukast is not a rescue medicine for acute asthma or status asthmaticus.
The following conditions are
contraindicated with this drug:
Suicidal thoughts
Known aspirin sensitivity
Increased eosinophil in the blood
It is also used before exercise to prevent breathing problems during exercise (Exercise induced bronchospasm).
Montelukast is also used to relieve symptoms of hay fever and Allergic Rhinitis (such as sneezing, stuffy/runny/itchy nose) and Persistent cough (COPD).
Prophylaxis and maintenance
treatment of Chronic Asthma
Oral
Adult:
10 mg once daily in the evening.
Children
<12 months: Safety and
efficacy not established
Children 12-23 months: 4 mg
(granules) once daily in evening
2-5 years: 4 mg (chewable tablet
or orodispersible tablet) once daily in evening
6-14 years: 5 mg (chewable tablet
or orodispersible tablet) once daily in evening
15 years and Older: 10 mg tablet
once daily in evening
· Prophylaxis
of Exercise-Induced Bronchospasm
Adult:
10 mg at least 2 hr prior to
exercise; do not take additional doses w/in 24 hr.
Children:
6-14 years: 5 mg 2 hours before
exercise; do not take additional dose within 24 hours
15 years and Older: 10 mg 2 hours
before exercise; do not take additional dose within 24 hours
Note: An
additional dose of montelukast should not be taken within 24 hours of a
previous dose. Patients already taking one tablet daily for another indication
(including chronic asthma) should not take an additional dose to prevent
exercise induced bronchospasm. All patients should have available for rescue a
short-acting β-agonist.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020829s63-20830s64-21409s40lbl.pdf
https://reference.medscape.com/drug/singulair-montelukast-343440#5
https://www.rxlist.com/singulair-drug.htm#warnings
https://www.drugs.com/cdi/montelukast-tablets.html
Note: For informational
purposes only. Consult your textbook for advising your patients.
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