Treatment guidelines for type 2 diabetes mellitus (T2DM) recommend initiating pharmacotherapy with an oral antidiabetic drug (OAD) to reduce hyperglycaemia when diet and exercise are inadequate. International guidelines recommend metformin as the first OAD, whereas Japanese guidelines recognize that other OADs may be more appropriate i...

Diabetes Care: American Diabetes Association Journal The standard pharmacotherapy for management of type 2 diabetes mellitus (T2DM) involves initiation with monotherapy (usually metformin) unless there are contraindications or intolerance, followed by sequential addition of other single agents, when target glycaemic control is not achieved o...